Ellison Medical Institute, a Los Angeles cancer research and treatment center backed by Oracle co-founder Larry Ellison, will permanently lay off 88 workers early next year, according to a state filing.

    The layoffs at the institute’s facility at 12414 Exposition Blvd. are scheduled to take effect Jan. 3, according to a Worker Adjustment and Retraining Notification filed Nov. 4 with the California Employment Development Department.

    The notice did not specify which positions would be eliminated or the reason for the layoffs.

    The institute did not immediately respond to a request for comment.

    The institute, led by founding CEO Dr. David Agus, describes itself as a medical research and development center focused on artificial intelligence, molecular analytics and the prevention, detection and treatment of cancer and other complex diseases.

    Its Los Angeles campus includes a preventive medicine and cancer clinic, research laboratories, clinical trial units, a health policy think tank and community education programs.

    The institute opened in 2016 as the Lawrence J. Ellison Institute for Transformative Medicine of USC, following a $200 million donation from Ellison. It later became independent of USC.

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