The secret CIA MKULTRA Project ran from 1953 to 1973 and encompasses thousands of individual experiments with 149 Subprojects. Many of the people that were experimented on were totally unaware of the project. Many were prisoners, psychiatric patients, and volunteers that were lied to about their involvement and nature of the research that they agreed to. The program was headed by Sidney Gottlieb, a master chemist and future CIA poison master, under the direct supervision of Allan Dulles, the then Director of the CIA. https://en.wikipedia.org/wiki/Sidney_Gottlieb
Gottlieb had a very interesting career as outlined briefly in the Wikipedia article. Further reading on his career is encouraged, and provided here in Stephen Kinzers harrowing research: https://archive.org/details/kinzer-stephen-poisonerin-chief
Previous to MKULTRA was Project BLUEBIRD, later renamed Project ARTICHOKE, which among other things was looking into making a subject an assassin, through the use of mind bending drugs, torture, forced hypnosis and mind control. Both ARTICHOKE and MKULTRA were spawned from the 1947 Project CHATTER, the first of its kind to use psychotropic drugs such as LSD on human subjects. The Project CHATTER ended in 1953 when it's main experiments were folded into MKULTRA.
List of 149 MKULTRA Subprojects
https://www.illuminatirex.com/list-of-mkultra-subprojects/
MKULTRA wikipedia article
https://en.m.wikipedia.org/wiki/MKUltra
Various supplemental articles
https://thecollector.vercel.app/project-mk-ultra-cia-secret-experiments/
https://www.grunge.com/53425/untold-truth-project-mkultra/
https://www.unz.com/article/mk-ultra-never-ended-it-just-went-mainstream/
Posted by seekerofthesublime