Denmark close to wiping out leading cancer-causing HPV strains after vaccine roll-out
A nationwide study suggests infections with human papillomavirus (HPV) types 16 and 18 have been virtually eliminated since vaccination began in 2008 – protecting even unvaccinated women.
>What did you want to address in this study and why?
>Women in Denmark who were vaccinated in 2008 against human papillomavirus (HPV) as girls (~14 years) have reached screening age. Compared with previous generations, these women are expected to have a considerably lower risk of cervical cancer and it is pertinent to assess the new generations’ future need for screening. We tested up to three consecutive cervical cell samples of Danish women (22–30 years) vaccinated as girls, collected between 2017 and 2024.
>What have we learnt from this study?
>Infection with HPV types covered by the vaccine (HPV16/18) has been almost eliminated. Before vaccination, the prevalence of HPV16/18 was between 15–17%, which has decreased in vaccinated women to < 1% by 2021. However, about one-third of women still had HPV infection with non-vaccine high-risk HPV types, and new infections with these types were more frequent in vaccinated than in unvaccinated women.
>What are the implications of your findings for public health?
>The HPV vaccine has been effective in reducing infections with vaccine-covered HPV types (HPV16/18), the HPV types responsible for over 70% of cervical cancer. Still, the high but steady proportion of women infected with high-risk HPV types not covered by the vaccine indicate a need for less intensive but continued screening of these generations.
Laetitian on
I was going to ask why this is political, then I remembered I just saw a 40 minute Joe Rogan clip about vaccines.
I still don’t know why this is political.
Unrelated question, are there any men experienced with HPV vaccination as adults? Is it done? Useful? Do doctors tend to make a fuzz about it?
BlackCat159 on
WAOW. As turbulent as the world may be, it’s great to see the progress made in medicine. I hope one day all infectious diseases will be eliminated in this way.
3 Comments
Link to original study: [https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2025.30.27.2400820](https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2025.30.27.2400820)
>Key public health message
>What did you want to address in this study and why?
>Women in Denmark who were vaccinated in 2008 against human papillomavirus (HPV) as girls (~14 years) have reached screening age. Compared with previous generations, these women are expected to have a considerably lower risk of cervical cancer and it is pertinent to assess the new generations’ future need for screening. We tested up to three consecutive cervical cell samples of Danish women (22–30 years) vaccinated as girls, collected between 2017 and 2024.
>What have we learnt from this study?
>Infection with HPV types covered by the vaccine (HPV16/18) has been almost eliminated. Before vaccination, the prevalence of HPV16/18 was between 15–17%, which has decreased in vaccinated women to < 1% by 2021. However, about one-third of women still had HPV infection with non-vaccine high-risk HPV types, and new infections with these types were more frequent in vaccinated than in unvaccinated women.
>What are the implications of your findings for public health?
>The HPV vaccine has been effective in reducing infections with vaccine-covered HPV types (HPV16/18), the HPV types responsible for over 70% of cervical cancer. Still, the high but steady proportion of women infected with high-risk HPV types not covered by the vaccine indicate a need for less intensive but continued screening of these generations.
I was going to ask why this is political, then I remembered I just saw a 40 minute Joe Rogan clip about vaccines.
I still don’t know why this is political.
Unrelated question, are there any men experienced with HPV vaccination as adults? Is it done? Useful? Do doctors tend to make a fuzz about it?
WAOW. As turbulent as the world may be, it’s great to see the progress made in medicine. I hope one day all infectious diseases will be eliminated in this way.